Imidazoline Receptor
Imidazoline receptors are a class of non-adrenergic receptors predominantly found in the central nervous system and peripheral tissues. They are primarily identified in three types: I1, I2, and I3, each with distinct physiological roles and tissue distributions. I1 receptors are involved in regulating blood pressure and exhibit therapeutic potential for treating hypertension. I2 receptors are implicated in pain modulation, neuroprotection, and mood regulation, offering targets for analgesic and antidepressant drugs. I3 receptors are associated with insulin secretion from pancreatic cells. Due to their diverse roles, imidazoline receptors are attractive pharmacological targets, especially for developing treatments for cardiovascular disorders, depression, and diabetes.