Chiral Resolving Reagents Overview

The chiral resolution is also known as optical resolution or racemic resolution. In stereochemistry, separating racemic compounds into two different mirror isomers is an important tool for producing optically active drugs.
The chemical splitting method is suitable for molecules that contain easily reactive groups and also easily regenerate the original enantiomeric compound after the reaction. The most common easily reactive groups are acid-base groups, which is because acid-base reactions are very easy, the resulting salts are relatively easy to crystallize, cheap and easy to obtain, or can be easily recycled, and also relatively easy to make spin pure. Commonly used acidic splitting agents are: (+)-tartaric acid, (+)-camphoric acid, (+)-camphor-10-sulfonic acid, L-(+)-glycine, etc.; commonly used basic splitting agents are: (-)-strychnine, (-)-sanguinarine, D-(-)-ephedrine, (+) or ( -)-α-phenylethylamine, etc.

Cat No. Product Name CAS No. Purity Order
L038489 (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid 71607-31-3 ≥ 95% Inquiry
L023079 2-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy) 40248-63-3 ≥ 95% Inquiry
L023056 (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic a 20445-31-2 ≥ 95% Inquiry
L002284 (S)-(+)-1-(1-Naphthyl)ethyl isocyanate 73671-79-1 ≥ 95% Inquiry
M088052 (S)-(-)-N,N-DIMETHYL-1-PHENETHYLAMINE 17279-31-1 ≥ 95% Inquiry
M066529 (S)-(-)-1-Phenylethyl isocyanate 14649-03-7 ≥ 95% Inquiry
R043813 (S)-Camphanic Acid 13429-83-9 ≥ 95% Inquiry
R034213 (-)-(1R)-Menthyl Chloroformate 14602-86-9 ≥ 95% Inquiry