Chiral Resolving Reagents Overview
The chiral resolution is also known as optical resolution or racemic resolution. In stereochemistry, separating racemic compounds into two different mirror isomers is an important tool for producing optically active drugs.
The chemical splitting method is suitable for molecules that contain easily reactive groups and also easily regenerate the original enantiomeric compound after the reaction. The most common easily reactive groups are acid-base groups, which is because acid-base reactions are very easy, the resulting salts are relatively easy to crystallize, cheap and easy to obtain, or can be easily recycled, and also relatively easy to make spin pure. Commonly used acidic splitting agents are: (+)-tartaric acid, (+)-camphoric acid, (+)-camphor-10-sulfonic acid, L-(+)-glycine, etc.; commonly used basic splitting agents are: (-)-strychnine, (-)-sanguinarine, D-(-)-ephedrine, (+) or ( -)-α-phenylethylamine, etc.
Cat No. | Product Name | CAS No. | Purity | Order |
---|---|---|---|---|
L038489 | (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid | 71607-31-3 | ≥ 95% | Inquiry |
L023079 | 2-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy) | 40248-63-3 | ≥ 95% | Inquiry |
L023056 | (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic a | 20445-31-2 | ≥ 95% | Inquiry |
L002284 | (S)-(+)-1-(1-Naphthyl)ethyl isocyanate | 73671-79-1 | ≥ 95% | Inquiry |
M088052 | (S)-(-)-N,N-DIMETHYL-1-PHENETHYLAMINE | 17279-31-1 | ≥ 95% | Inquiry |
M066529 | (S)-(-)-1-Phenylethyl isocyanate | 14649-03-7 | ≥ 95% | Inquiry |
R043813 | (S)-Camphanic Acid | 13429-83-9 | ≥ 95% | Inquiry |
R034213 | (-)-(1R)-Menthyl Chloroformate | 14602-86-9 | ≥ 95% | Inquiry |