Chiral Reagents Overview
Chirality is one of the essential properties of nature. Biological macromolecules as the important basis of life activities, such as proteins, polysaccharides, nucleic acids and enzymes, are almost all chiral, and these chiral molecules often have important physiological functions in the body.
At present, most of the drugs used are organic small molecules composed of less than 50 atoms, and a large part of them are also chiral. Their pharmacological effects are achieved by strict chiral matching and molecular recognition with macromolecules in vivo. There are significant differences in pharmacological activity, metabolic process and toxicity of enantiomers of chemical reagents containing chiral factors in the human body. At present, the research of chiral reagents has become one of the main directions of international new drug research.