CaMK
Calcium/calmodulin-dependent protein kinase (CaMK) refers to a family of serine/threonine-specific kinases activated by the calcium/calmodulin complex. These kinases play crucial roles in various cellular processes, including metabolism, gene transcription, memory formation, and muscle contraction. CaMK is particularly significant in the nervous system, where it is essential for synaptic plasticity and learning. Due to its involvement in these critical functions, dysregulation of CaMK activity is associated with neurological disorders, cardiovascular diseases, and cancer. Targeting CaMKs therapeutically offers the potential for treating these conditions by modulating calcium signaling pathways. Ongoing research focuses on developing selective CaMK inhibitors to achieve therapeutic benefits while minimizing side effects.