Casein Kinase

Casein kinase is a family of serine/threonine-specific protein kinases that play vital roles in regulating cellular processes such as cell division, differentiation, and survival. There are two main types: Casein Kinase 1 (CK1) and Casein Kinase 2 (CK2), each with distinct cellular functions and substrates. CK1 is involved in various signaling pathways, including Wnt signaling and circadian rhythms, while CK2 participates in cell cycle control, DNA repair, and apoptosis. Their ubiquitous expression and integral roles in key signaling pathways make casein kinases crucial targets for therapeutic intervention. Modulating their activity has potential implications in treating diseases like cancer, neurodegenerative disorders, and other conditions where abnormal cell signaling is a factor.