Isotope Labeled Inhibitors

Isotope-labeled inhibitors are molecules used in research to study enzyme, receptor, or protein activity. These inhibitors contain isotopes like carbon-14 or tritium, allowing their detection in biological systems. By incorporating these isotopes, researchers can track the binding of inhibitors to proteins, aiding in drug development. Isotope-labeled inhibitors are crucial in determining binding affinities and understanding metabolic pathways. They are used in techniques like autoradiography and liquid scintillation counting, providing insights into the mechanisms of action of drugs and their fate in biological systems. This information is vital for optimizing drug design and understanding how drugs interact with their targets, aiding in developing more effective treatments.