Enrofloxacin

  • CAT Number: A000520
  • CAS Number: 93106-60-6
  • Molecular Formula: C19H22FN3O3
  • Molecular Weight: 359.4
  • Purity: ≥95%
Inquiry Now

Enrofloxacin is a fluoroquinolone antibiotic sold by the Bayer Corporation. It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20–30 minutes of exposure. Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and is active in both stationary and growth phases of bacterial replication.

Catalog Number A000520
CAS Number 93106-60-6
Molecular Formula

C19H22FN3O3

Purity 95%
Storage -20°C
InChI 1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChIKey SPFYMRJSYKOXGV-UHFFFAOYSA-N
SMILES CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
Reference

1: Lu X, Li Y, Thunders M, Matthew C, Wang X, Ai X, Zhou X, Qiu J. Effect of
enrofloxacin on the proteome of earthworms. Sci Total Environ. 2017 Nov
9;616-617:531-542. doi: 10.1016/j.scitotenv.2017.10.275. [Epub ahead of print]
PubMed PMID: 29128840.
<br>

2: Kirby A, Lewbart GA, Hancock-Ronemus A, Papich MG. Pharmacokinetics of
enrofloxacin and ciprofloxacin in Atlantic horseshoe crabs (Limulus polyphemus)
after single injection. J Vet Pharmacol Ther. 2017 Oct 25. doi:
10.1111/jvp.12462. [Epub ahead of print] PubMed PMID: 29067728.
<br>

3: Rico A, Zhao W, Gillissen F, Lürling M, Van den Brink PJ. Effects of
temperature, genetic variation and species competition on the sensitivity of
algae populations to the antibiotic enrofloxacin. Ecotoxicol Environ Saf. 2017
Oct 19;148:228-236. doi: 10.1016/j.ecoenv.2017.10.010. [Epub ahead of print]
PubMed PMID: 29055776.
<br>

4: Roth N, Mayrhofer S, Gierus M, Weingut C, Schwarz C, Doupovec B, Berrios R,
Domig KJ. Effect of an organic acids based feed additive and enrofloxacin on the
prevalence of antibiotic-resistant E. coli in cecum of broilers. Poult Sci. 2017
Sep 1;96(11):4053-4060. doi: 10.3382/ps/pex232. PubMed PMID: 29050428.
<br>

5: Ikem A, Lin CH, Broz B, Kerley M, Thi HL. Occurrence of enrofloxacin in
overflows from animal lot and residential sewage lagoons and a receiving-stream.
Heliyon. 2017 Oct 10;3(10):e00409. doi: 10.1016/j.heliyon.2017.e00409.
eCollection 2017 Oct. PubMed PMID: 29034336; PubMed Central PMCID: PMC5635953.
<br>

6: Li J, Hao H, Cheng G, Liu C, Ahmed S, Shabbir MAB, Hussain HI, Dai M, Yuan Z.
Microbial Shifts in the Intestinal Microbiota of Salmonella Infected Chickens in
Response to Enrofloxacin. Front Microbiol. 2017 Sep 8;8:1711. doi:
10.3389/fmicb.2017.01711. eCollection 2017. PubMed PMID: 28943868; PubMed Central
PMCID: PMC5596078.
<br>

7: Li J, Hao H, Cheng G, Wang X, Ahmed S, Shabbir MAB, Liu Z, Dai M, Yuan Z. The
effects of different enrofloxacin dosages on clinical efficacy and resistance
development in chickens experimentally infected with Salmonella Typhimurium. Sci
Rep. 2017 Sep 15;7(1):11676. doi: 10.1038/s41598-017-12294-7. PubMed PMID:
28916830; PubMed Central PMCID: PMC5601478.
<br>

8: Carrascosa A, Gutierrez L, De la Pe&#241;a A, Candanosa IE, Tapia G, Sumano H.
Efficacy of a New Recrystallized Enrofloxacin Hydrochloride-Dihydrate against
Leptospirosis in a Hamster Model. Antimicrob Agents Chemother. 2017 Oct
24;61(11). pii: e01285-17. doi: 10.1128/AAC.01285-17. Print 2017 Nov. PubMed
PMID: 28874381; PubMed Central PMCID: PMC5655069.
<br>

9: Pan M, Li S, Wang J, Sheng W, Wang S. Development and Validation of a
Reproducible and Label-Free Surface Plasmon Resonance Immunosensor for
Enrofloxacin Detection in Animal-Derived Foods. Sensors (Basel). 2017 Aug
30;17(9). pii: E1984. doi: 10.3390/s17091984. PubMed PMID: 28867795; PubMed
Central PMCID: PMC5621032.
<br>

10: Parpounas A, Litskas V, Hapeshi E, Michael C, Fatta-Kassinos D. Assessing the
presence of enrofloxacin and ciprofloxacin in piggery wastewater and their
adsorption behaviour onto solid materials, with a newly developed chromatographic
method. Environ Sci Pollut Res Int. 2017 Aug 25. doi: 10.1007/s11356-017-9849-9.
[Epub ahead of print] PubMed PMID: 28842853.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!