Luliconazole - CAS 187164-19-8

Luliconazole is an azole antifungal drug. As a 1% topical cream, luliconazole is indicated for the treatment of athlete/’s foot, jock itch, and ringworm caused by Trichophyton rubrum and Epidermophyton floccosum. Luliconazole is an antifungal that belongs to the azole class. Although the exact mechanism of action against dermatophytes is unknown, luliconazole appears to inhibit ergosterol synthesis by inhibiting the enzyme lanosterol demethylase. Inhibition of this enzyme/’s activity by azoles results in decreased amounts of ergosterol, a constituent of fungal cell membranes, and a corresponding accumulation of lanosterol. (copies from http://www.rxlist.com/luzu-drug/clinical-pharmacology.htm).

Catalog Number: A000163

CAS Number: 187164-19-8

PubChem Substance ID:355040387

Molecular Formula: C14H9Cl2N3S2

Molecular Weight:354.28

Purity: ≥95%

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Synonym

Synonyms	187164-19-8; Lulicon; Luzu; NND-502; PR-2699

Property

Molecular Formula:	C14H9Cl2N3S2
Molecular Weight	354.28
Target:	Antibiotic
Solubility	>17.7mg/mL in DMSO
Purity	≥95%
Storage	Store at -20°C

Computed Descriptor

InChI	1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
InChIKey	YTAOBBFIOAEMLL-REQDGWNSSA-N
SMILES	C1C(SC(=C(C#N)N2C=CN=C2)S1)C3=C(C=C(C=C3)Cl)Cl