Vancomycin hydrochloride

• CAT Number: I013964
• CAS Number: 1404-93-9
• Molecular Formula: C₆₆H₇₆Cl₃N₉O₂₄
• Molecular Weight: 1485.72
• Purity: ≥95%
• Target: BacterialAutophagy
• Solubility: DMSO: 24 mg/mL
• InChI: InChI=1S/C66H75Cl2N9O24.ClH/c1-23-56(87)66(5,70)21-42(96-23)100-54-52(86)51(85)40(22-78)99-64(54)101-53-38-16-27-17-39(53)98-37-12-9-26(15-32(37)68)50(84)48-61(92)75-46(63(94)95)30-18-28(79)19-35(81)43(30)29-13-24(7-10-34(29)80)44(58(89)76-48)74-59(90)45(27)73-57(88)33(20-41(69)82)72-60(91)47(77-62(93)55(71-6)65(2,3)4)49(83)25-8-11-36(97-38)31(67)14-25;/h7-19,23,33,40,42,44-52,54-56,64,71,78-81,83-87H,20-22,70H2,1-6H3,(H2,69,82)(H,72,91)(H,73,88)(H,74,90)(H,75,92)(H,76,89)(H,77,93)(H,94,95);1H/t23-,33-,40+,42-,44+,45+,46-,47+,48-,49+,50+,51+,52-,54+,55-,56+,64-,66-;/m0./s1
• InChIKey: PRBZNSSZHLUGTK-FHHNGZMLSA-N
• SMILES: CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(C(C)(C)C)NC)O)Cl)CO)O)O)(C)N)O.Cl

Vancomycin hydrochloride (Cat.No:I013964) is an antibiotic used to treat serious bacterial infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. It inhibits bacterial cell wall synthesis, leading to cell death. Vancomycin hydrochloride is administered intravenously and is a critical tool in combating antibiotic-resistant infections.

Reference

[1]. Rybak MJ, et al. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S35-9.[2]. Watanakunakorn C, et al. Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18.[3]. Warren CA, et al. Vancomycin treatment//’s association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. Antimicrob Agents Chemother. 2013 Feb;57(2):689-96.