Tebipenem

• CAT Number: I002067
• CAS Number: 161715-21-5
• Molecular Formula: C16H21N3O4S2
• Molecular Weight: 383.49
• Purity: ≥95%
• Target: Antibiotic
• Solubility: DMSO: ≥ 45 mg/mL, H2O: ≥ 6.2 mg/mL
• Storage: Store at -20°C

Tebipenem(LJC-11036) is a broad spectrum orally administered antibiotic; exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin; Km and kcat values are 0.8 μM and 0.03 min(-1) for Blac.

Reference

[1]. Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8.
[2]. Seenama C, et al. In vitro activity of tebipenem against Burkholderia pseudomallei. Int J Antimicrob Agents. 2013 Oct;42(4):375.