Where to Buy 120788-07-0

CAT Number: R034765
CAS Number: 120788-07-0
Molecular Formula: C₁₂H₁₅NO₅S₃
Molecular Weight: 349.45
Purity: ≥95%

Sulopenem, also known as CP-70429, is a potent beta-lactamase inhibitor.Sulopenem showed potent antibacterial activity against gram-positive and gram-negative bacteria except Pseudomonas aeruginosa and Xanthomonas maltophilia. CP-70,429 was stable to various types of beta-lactamases except for the enzyme from X. maltophilia and was 16- to 128-fold more active than the other compounds against beta-lactamase-producing strains of Enterobacter cloacae and Citrobacter freundii.

Catalog Number	R034765
CAS Number	120788-07-0
Molecular Formula	C₁₂H₁₅NO₅S₃
Purity	95%
Target	beta-lactamase inhibitor
Storage	-20°C
Reference	</br>1:Comparative antipneumococcal activities of sulopenem and other drugs. Kosowska-Shick K, Ednie LM, McGhee P, Appelbaum PC.Antimicrob Agents Chemother. 2009 Jun;53(6):2239-47. doi: 10.1128/AAC.01531-08. Epub 2009 Mar 23. PMID: 19307366 Free PMC Article</br>2:Antianaerobic activity of sulopenem compared to six other agents. Ednie LM, Appelbaum PC.Antimicrob Agents Chemother. 2009 May;53(5):2163-70. doi: 10.1128/AAC.01557-08. Epub 2009 Feb 17. PMID: 19223615 Free PMC Article</br>3:Reduction of in-source collision-induced dissociation and thermolysis of sulopenem prodrugs for quantitative liquid chromatography/electrospray ionization mass spectrometric analysis by promoting sodium adduct formation. Wujcik CE, Kadar EP.Rapid Commun Mass Spectrom. 2008 Oct;22(20):3195-206. doi: 10.1002/rcm.3722. PMID: 18803331 </br>4:[In vitro activities of sulopenem, a new parenteral penem, against anaerobes]. Watanabe K, Kato N, Tanaka-Bandoh K, Tanaka Y, Kato H, Ueno K.Jpn J Antibiot. 1996 Apr;49(4):367-76. Japanese. PMID: 8786627 </br>5:[In vitro and in vivo antibacterial activities of sulopenem, a new penem antibiotic]. Komoto A, Otsuki M, Nishino T.Jpn J Antibiot. 1996 Apr;49(4):352-66. Japanese. Erratum in: Jpn J Antibiot 1996 May;49(5):508. PMID: 8786626 </br>6:[Antibacterial activity of sulopenem, a new parenteral penem antibiotic]. Inoue E, Komoto E, Taniyama Y, Mitsuhashi S.Jpn J Antibiot. 1996 Apr;49(4):338-51. Japanese. PMID: 8786625 </br>7:[In vitro antibacterial activity of a new parenteral penem, sulopenem]. Yoshida T, Tateda E, Hiramatsu K, Yokota T.Jpn J Antibiot. 1996 Apr;49(4):324-37. Japanese. PMID: 8786624 </br>8:[In vitro and in vivo activities of sulopenem compared with those of imipenem and cephalosporins]. Nagashima M, Goto S, Yoshida T, Matsunaga T, Shimohira H, Ogawa M.Jpn J Antibiot. 1996 Apr;49(4):303-23. Japanese. PMID: 8786623

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