Sulfanilamide

  • CAT Number: I004407
  • CAS Number: 63-74-1
  • Molecular Formula: C6H8N2O2S
  • Molecular Weight: 172.2
  • Purity: ≥95%
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Sulfonamides(Cat No.:I004407) represent a widely utilized class of antibacterial medications with several advantageous attributes. They are notable for their broad-spectrum antibacterial activity, making them effective against a variety of bacterial infections. Sulfonamides are often administered orally, ensuring convenient delivery. Some variants, like Sulfadiazine (S.D), possess the unique capability to penetrate the blood-brain barrier, reaching the cerebrospinal fluid to treat central nervous system infections.

Catalog Number I004407
CAS Number 63-74-1
Molecular Formula

C6H8N2O2S

Purity 95%
Target Antibiotic
Solubility DMSO: ≥ 30 mg/mL
Storage 2-8°C
IUPAC Name 4-aminobenzenesulfonamide
InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKey FDDDEECHVMSUSB-UHFFFAOYSA-N
SMILES C1=CC(=CC=C1N)S(=O)(=O)N
Reference

</br>1:Pharmacokinetics of the antimicrobial drug sulfanilamide is altered in a preclinical model of vascular calcification. Brandoni A, Torres AM.Clin Exp Pharmacol Physiol. 2017 Jan 2. doi: 10.1111/1440-1681.12722. [Epub ahead of print] PMID: 28042884 </br>2:Automated Enrichment of Sulfanilamide in Milk Matrices by Utilization of Aptamer-Linked Magnetic Particles. Fischer C, Kallinich C, Klockmann S, Schrader J, Fischer M.J Agric Food Chem. 2016 Dec 7;64(48):9246-9252. Epub 2016 Nov 28. PMID: 27933990 </br>3:Peculiar behavior of starch 2,3-dialdehyde towards sulfanilamide and sulfathiazole. Keshk SM, Ramadan AM, Al-Sehemi AG, Yousef el S, Bondock S.Carbohydr Polym. 2016 Nov 5;152:624-31. doi: 10.1016/j.carbpol.2016.07.061. Epub 2016 Jul 18. PMID: 27516312 </br>4:Ag loaded WO3 nanoplates for efficient photocatalytic degradation of sulfanilamide and their bactericidal effect under visible light irradiation. Zhu W, Liu J, Yu S, Zhou Y, Yan X.J Hazard Mater. 2016 Nov 15;318:407-16. doi: 10.1016/j.jhazmat.2016.06.066. Epub 2016 Jul 1. PMID: 27450332 </br>5:Towards a molecular level understanding of the sulfanilamide-soil organic matter-interaction. Ahmed AA, Thiele-Bruhn S, Leinweber P, Kühn O.Sci Total Environ. 2016 Jul 15;559:347-55. doi: 10.1016/j.scitotenv.2016.03.136. Epub 2016 Apr 16. PMID: 27088516 </br>6:Copper-promoted circumneutral activation of H2O2 by magnetic CuFe2O4 spinel nanoparticles: Mechanism, stoichiometric efficiency, and pathway of degrading sulfanilamide. Feng Y, Liao C, Shih K.Chemosphere. 2016 Jul;154:573-82. doi: 10.1016/j.chemosphere.2016.04.019. Epub 2016 Apr 14. PMID: 27085318 </br>7:Oral absorption profiles of sulfonamides in Shiba goats: a comparison among sulfadimidine, sulfadiazine and sulfanilamide. Elbadawy M, Ishihara Y, Aboubakr M, Sasaki K, Shimoda M.J Vet Med Sci. 2016 Jul 1;78(6):1025-9. doi: 10.1292/jvms.15-0601. Epub 2016 Mar 24. PMID: 27010464 Free PMC Article</br>8:Antibiotic sulfanilamide biodegradation by acclimated microbial populations. Liao X, Li B, Zou R, Xie S, Yuan B.Appl Microbiol Biotechnol. 2016 Mar;100(5):2439-47. doi: 10.1007/s00253-015-7133-9. Epub 2015 Nov 13. PMID: 26563551 </br>9:Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one Sulfanilamide. Idemudia OG, Sadimenko AP, Afolayan AJ, Hosten EC.Bioinorg Chem Appl. 2015;2015:717089. doi: 10.1155/2015/717089. Epub 2015 May 27. PMID: 26106285 Free PMC Article</br>10:Sensitive simultaneous determination of three sulfanilamide artificial sweeters by capillary electrophoresis with on-line preconcentration and contactless conductivity detection. Yang L, Zhou S, Xiao Y, Tang Y, Xie T.Food Chem. 2015 Dec 1;188:446-51. doi: 10.1016/j.foodchem.2015.04.060. Epub 2015 May 8. PMID: 26041216

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