For research use only. Not for therapeutic Use.
SARM1-IN-2（Cat No.:I043848）is a selective small molecule inhibitor targeting SARM1 (Sterile alpha and TIR motif-containing protein 1), a key regulator of neuroinflammation and axonal degeneration. SARM1 plays a critical role in mediating nerve cell death in neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and peripheral neuropathies. By inhibiting SARM1, this compound prevents axonal injury and neuronal degeneration, offering potential therapeutic benefits in conditions characterized by neuroinflammation and nerve damage. SARM1-IN-2 is being explored for its ability to protect neurons and slow the progression of neurodegenerative disorders.
| CAS Number | 2396592-52-0 |
| Synonyms | 5-[(6-methoxy-2-methylquinolin-5-yl)amino]-2-methyl-3-oxo-1,2-thiazole-4-carbonitrile |
| Molecular Formula | C16H14N4O2S |
| Purity | ≥95% |
| IUPAC Name | 5-[(6-methoxy-2-methylquinolin-5-yl)amino]-2-methyl-3-oxo-1,2-thiazole-4-carbonitrile |
| InChI | InChI=1S/C16H14N4O2S/c1-9-4-5-10-12(18-9)6-7-13(22-3)14(10)19-15-11(8-17)16(21)20(2)23-15/h4-7,19H,1-3H3 |
| InChIKey | YCKJOVSJCNUPNR-UHFFFAOYSA-N |
| SMILES | CC1=NC2=C(C=C1)C(=C(C=C2)OC)NC3=C(C(=O)N(S3)C)C#N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
