Lanatoside C

  • CAT Number: I002290
  • CAS Number: 17575-22-3
  • Molecular Formula: C49H76O20
  • Molecular Weight: 985.12
  • Purity: ≥95%
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<p style=/line-height:25px/>Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells.<br>Target:<br>in vitro: Dose-dependent reduction in dengue viral RNA and viral proteins synthesis were also observed upon treatment with increasing concentrations of Lanatoside C. Time of addition study indicated that Lanatoside C inhibits the early processes of the dengue virus replication cycle. Furthermore, Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71. Lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses. [2]</p>

Catalog Number I002290
CAS Number 17575-22-3
Molecular Formula

C49H76O20

Purity 95%
Solubility 10 mM in H2O
Storage Store at -20°C
Reference

<p style=/line-height:25px/>
<br>[1]. Crommentuijn MH, et al. Intracranial AAV-sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma. Mol Oncol. 2015 Dec 11. pii: S1574-7891(15)00226-4.

<br>[2]. Cheung YY, et al. Antiviral activity of lanatoside C against dengue virus infection. Antiviral Res. 2014 Nov;111:93-99.

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