Roxithromycin - CAS 80214-83-1

Roxithromycin is a semisynthetic macrolide antibiotic and is sparingly soluble in aqueous solution ( 0.019 mg/mL).
Macrolide antibiotics inhibit bacterial growth by targeting the 50S ribosomal subunit preventing peptide bond formation and translocation during protein synthesis. Resistance to roxithromycin is commonly attributed to mutations in 50S rRNA preventing roxithromycin binding allowing the cell to synthesize proteins free of error.

Catalog Number: A000411

CAS Number: 80214-83-1

PubChem Substance ID:355038649

Molecular Formula: C₄₁H₇₆N₂O₁₅

Molecular Weight:837.05

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsRoxl-150

Property

Molecular Formula: C₄₁H₇₆N₂O₁₅
Molecular Weight837.05
Purity≥95%
Storage3 years -20C powder
MDLMFCD00214389

Computed Descriptor

InChIInChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31-/t22-,23
InChIKeyRXZBMPWDPOLZGW-HEWSMUCTSA-N
SMILESCCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O