Ampicillin (Cat.No:I004612) is a broad-spectrum antibiotic used to treat various bacterial infections such as pneumonia, bronchitis, urinary tract infections, and meningitis. It works by preventing the bacterial cell wall from forming and thus inhibiting bacterial growth. Ampicillin is available in various forms such as capsules, tablets, and injections.
| Catalog Number | I004612 |
| CAS Number | 69-53-4 |
| Molecular Formula | C16H19N3O4S |
| Purity | 95% |
| Target | Antibacterial |
| Solubility | 10 mM in DMSO |
| Storage | 3 years -20℃ powder |
| IUPAC Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChI | InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1 |
| InChIKey | AVKUERGKIZMTKX-NJBDSQKTSA-N |
| SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C |
| Reference | </br>1:Occurrence of ampicillin-resistant Enterococcus faecium carrying esp gene in pet animals: An upcoming threat for pet lovers. Abdel-Moein KA, El-Hariri MD, Wasfy MO, Samir A.J Glob Antimicrob Resist. 2017 May 10;9:115-117. doi: 10.1016/j.jgar.2017.02.011. [Epub ahead of print] PMID: 28499907 </br>2:Ampicillin-incorporated alginate-chitosan fibers from microfluidic spinning and for vitro release. Zhang X, Huang C, Zhao Y, Jin X.J Biomater Sci Polym Ed. 2017 May 10:1-46. doi: 10.1080/09205063.2017.1329914. [Epub ahead of print] PMID: 28490251 </br>3:Ampicillin Mineralization by Denitrifying Process: Kinetic and Metabolic Effects. Islas-García I, Romo-Gómez C, de María Cuervo-López F.Appl Biochem Biotechnol. 2017 Apr 29. doi: 10.1007/s12010-017-2483-7. [Epub ahead of print] PMID: 28455806 </br>4:Successful treatment of multidrug-resistant Acinetobacter baumannii meningitis with ampicillin sulbactam in primary hospital. Sun L, Wang X, Li Z.Br J Neurosurg. 2017 Apr 21:1-4. doi: 10.1080/02688697.2017.1319907. [Epub ahead of print] PMID: 28431478 </br>5:Potentiometric, UV and <sup>1</sup>H NMR study on the interaction of Cu<sup>2+</sup> with ampicillin and amoxicillin in aqueous solution. Cardiano P, Crea F, Foti C, Giuffrè O, Sammartano S.Biophys Chem. 2017 May;224:59-66. doi: 10.1016/j.bpc.2017.04.001. Epub 2017 Apr 4. PMID: 28410941 </br>6:Droplet-based non-faradaic impedance sensors for assessment of susceptibility of Escherichia coli to ampicillin in 60 min. Ebrahimi A, Alam MA.Biomed Microdevices. 2017 Jun;19(2):27. doi: 10.1007/s10544-017-0165-4. PMID: 28405868 </br>7:Comparison between a Direct-Flow SPR Immunosensor for Ampicillin and a Competitive Conventional Amperometric Device: Analytical Features and Possible Applications to Real Samples. Tomassetti M, Merola G, Martini E, Campanella L, Sanzò G, Favero G, Mazzei F.Sensors (Basel). 2017 Apr 10;17(4). pii: E819. doi: 10.3390/s17040819. PMID: 28394296 Free PMC Article</br>8:Indole-Induced Activities of β-Lactamase and Efflux Pump Confer Ampicillin Resistance in <i>Pseudomonas putida</i> KT2440. Kim J, Shin B, Park C, Park W.Front Microbiol. 2017 Mar 14;8:433. doi: 10.3389/fmicb.2017.00433. eCollection 2017. PMID: 28352264 Free PMC Article</br>9:Efficacy of Telavancin Alone and in Combination with Ampicillin in a Rat Model of <i>Enterococcus faecalis</i> Endocarditis. Tran TT, Tam VH, Murray BE, Arias CA, Singh KV.Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02489-16. doi: 10.1128/AAC.02489-16. [Epub ahead of print] PMID: 28320712 </br>10:Recurrent trimethoprim-sulfamethoxazole-induced aseptic meningitis with associated ampicillin-induced myoclonic twitches . Fisse AL, Straßburger-Krogias K, Gold R, Ellrichmann G.Int J Clin Pharmacol Ther. 2017 Mar 14. doi: 10.5414/CP202957. [Epub ahead of print] PMID: 28291512 |
