RHEIN-8-GLUCOSIDE

• CAT Number: M015706
• CAS Number: 113443-70-2
• Molecular Formula: C21H16O11.Ca
• Molecular Weight: 484.4
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: calcium;3-carboxy-9,10-dioxo-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-1,8-diolate
• InChI: InChI=1S/C21H18O11.Ca/c22-5-11-16(26)18(28)19(29)20(32-11)7-1-2-9(23)14-13(7)15(25)8-3-6(21(30)31)4-10(24)12(8)17(14)27;/h1-4,11,16,18-20,22-24,26,28-29H,5H2,(H,30,31);/q;+2/p-2/t11-,16-,18+,19-,20+;/m1./s1
• InChIKey: XXVBCAMVOFYHJP-WJGQHNSASA-L
• SMILES: C1=CC(=C2C(=C1C3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2=O)C(=CC(=C4)C(=O)O)[O-])[O-].[Ca+2]

Rhein-8-glucoside calcium（Cat No.:M015706） is an anthraquinone compound derived from an ethanolic extract of Saussurea lappa root. It acts as a potent hPTP1B (protein tyrosine phosphatase 1B) inhibitor with an IC50 value of 11.5 μM. By inhibiting hPTP1B, it can modulate cellular signaling pathways and has potential therapeutic applications in various diseases, including diabetes and obesity. Additionally, Rhein-8-glucoside calcium exhibits antibacterial properties, making it a promising candidate for the development of new antibacterial agents.