Radezolid

  • CAT Number: I005232
  • CAS Number: 869884-78-6
  • Molecular Formula: C22H23FN6O3
  • Molecular Weight: 438.45
  • Purity: ≥95%
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<p style=/line-height:25px/>Radezolid (RX-1741) is a novel oxazolidinone antibiotic agent.<br>IC50 Value:<br>Target: Anti-infection<br>Radezolid is a novel oxazolidinone antibiotic being developed by Rib-X Pharmaceuticals, Inc. for the treatment of serious multi-drug–resistant infections. Radezolid has completed two phase-II clinical trials. One of these clinical trials was for uncomplicated skin and skin-structure infections (uSSSI) and the other clinical trial was for community acquired pneumonia (CAP). From Wikipedia</p>

Catalog Number I005232
CAS Number 869884-78-6
Molecular Formula

C22H23FN6O3

Purity 95%
Target Antibiotic
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

</br>1:Application of spectroscopic methods (FT-IR, Raman, ECD and NMR) in studies of identification and optical purity of radezolid. Michalska K, Gruba E, Mizera M, Lewandowska K, Bednarek E, Bocian W, Cielecka-Piontek J.Spectrochim Acta A Mol Biomol Spectrosc. 2017 Apr 20;183:116-122. doi: 10.1016/j.saa.2017.04.038. [Epub ahead of print] PMID: 28456082 </br>2:Enantioselective recognition of radezolid by cyclodextrin modified capillary electrokinetic chromatography and electronic circular dichroism. Michalska K, Gruba E, Bocian W, Cielecka-Piontek J.J Pharm Biomed Anal. 2017 May 30;139:98-108. doi: 10.1016/j.jpba.2017.01.041. Epub 2017 Feb 21. PMID: 28279932 </br>3:Cellular pharmacokinetics of the novel biaryloxazolidinone radezolid in phagocytic cells: studies with macrophages and polymorphonuclear neutrophils. Lemaire S, Tulkens PM, Van Bambeke F.Antimicrob Agents Chemother. 2010 Jun;54(6):2540-8. doi: 10.1128/AAC.01723-09. Epub 2010 Apr 12. PMID: 20385873 Free PMC Article</br>4:Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila. Lemaire S, Kosowska-Shick K, Appelbaum PC, Verween G, Tulkens PM, Van Bambeke F.Antimicrob Agents Chemother. 2010 Jun;54(6):2549-59. doi: 10.1128/AAC.01724-09. Epub 2010 Apr 12. PMID: 20385852 Free PMC Article

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