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Quisinostat (JNJ-26481585) 2HCl

Quisinostat (JNJ-26481585) 2HCl

  • CAT Number: I006448
  • CAS Number: 875320-31-3
  • Molecular Formula: C21H28Cl2N6O2
  • Molecular Weight: 467.39
  • Purity: ≥95%
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Quisinostat (JNJ-26481585) 2HCl (Cat.No:I006448) is an investigational histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. It works by blocking the activity of HDAC enzymes, leading to increased acetylation of histone proteins and altered gene expression. Quisinostat is being studied in clinical trials for its potential in treating various cancers, including hematologic malignancies and solid tumors.

Catalog Number I006448
CAS Number 875320-31-3
Molecular Formula

C21H28Cl2N6O2

Purity 95%
Target HDAC1
Storage 3 years -20℃ powder
IUPAC Name N-hydroxy-2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;dihydrochloride
InChI InChI=1S/C21H26N6O2.2ClH/c1-26-14-17(18-4-2-3-5-19(18)26)11-22-10-15-6-8-27(9-7-15)21-23-12-16(13-24-21)20(28)25-29;;/h2-5,12-15,22,29H,6-11H2,1H3,(H,25,28);2*1H
InChIKey NRUIZESXVMJDKR-UHFFFAOYSA-N
SMILES CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl

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