PROTOPINE HCl

  • CAT Number: T000140
  • CAS Number: 6164-47-2
  • Molecular Formula: C20H20ClNO5
  • Molecular Weight: 389.832
  • Purity: ≥95%
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<p>It is a Ca<sup>2+</sup> channel blocker; antiplatelet agent, a GABA binding activator. <br />It is also an antiarrhythmic with complex mechanism of action.</p><br />Alkaloid<!–C<SUB>20</SUB>H<SUB>19</SUB>NO<SUB>5</SUB>.HCl–>, from plants of the Fumariaceae family.</br><p>0.1 to 10 &mu;M increase the binding of <sup>3</sup>H-GABA with receptors in rat synaptosomes.</p></br>

Catalog Number T000140
CAS Number 6164-47-2
Molecular Formula

C20H20ClNO5

Purity 95%
Solubility Slightly in water<br>Practically not in alcohol
Storage Store at +4C, in dark place.
InChI InChI=1S/C20H19NO5.ClH/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17;/h2-3,7-8H,4-6,9-11H2,1H3;1H
InChIKey NWNVDSJZGYDVQW-UHFFFAOYSA-N
SMILES CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3.Cl
Reference

– Ko et al., <I>Jap. J. Pharmacol.</I> (1992) 58:1<br /><br />- Kardos et al., <I>Arzneim-Forsch.</I>(1986) 36(6):939-940<br /><br /><br /><br />

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