Pleuromutilin

• CAT Number: I001024
• CAS Number: 125-65-5
• Molecular Formula: C22H34O5
• Molecular Weight: 378.5
• Purity: ≥95%
• Target: Antibiotic
• Solubility: 10 mM in DMSO
• Storage: Store at 4°C
• IUPAC Name: [(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-hydroxyacetate
• InChI: InChI=1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
• InChIKey: ZRZNJUXESFHSIO-BKUNHTPHSA-N
• SMILES: C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CO)C

Pleuromutilin (Cat.No:I001024) is a natural antibiotic compound derived from certain fungal species. It exhibits potent antimicrobial activity against a wide range of Gram-positive bacteria, including drug-resistant strains like methicillin-resistant Staphylococcus aureus (MRSA). Pleuromutilin has been utilized in veterinary medicine and is currently being explored as a potential treatment option for human infections.

Reference

[1]. Shang RF et al. Synthesis and biological evaluation of new pleuromutilin derivatives as antibacterial agents. Molecules. 2014 Nov 19;19(11):19050-65.