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Oxytetracycline Dihydrate

Oxytetracycline Dihydrate

  • CAT Number: A000446
  • CAS Number: 6153-64-6
  • Molecular Formula: C22H28N2O11
  • Molecular Weight: 496.469
  • Purity: ≥95%
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Oxytetracycline was the second discovered tetracycline antibiotic.</br>The mechanism of oxytetracycline involves diffusing through a cell and binding to the 30s ribosomal subunit preventing peptide elongation and ultimately inhibiting protein synthesis. Resistance to oxytetracycline can be a result of inactivation by cell enzymes or pumping the antibiotic out of the cell upon entering.

Catalog Number A000446
CAS Number 6153-64-6
Molecular Formula

C22H28N2O11

Purity 95%
Storage 3 years -20C powder
IUPAC Name (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;dihydrate
InChI InChI=1S/C22H24N2O9.2H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);2*1H2/t12-,13-,14+,17+,21-,22+;;/m1../s1
InChIKey IMLJLCJZQLGHJS-JEKSYDDFSA-N
SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.O.O
Reference

<p>Chopra, Ian, and Marilyn Roberts. /Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance./ <em>Microbiology and Molecular Biology Reviews</em> (2001): 232-60. <em>Http://www.ncbi.nlm.nih.gov</em>. Web. 21 Aug. 2012.</p><p>Hubbard A.R., 2011, Evaluation of Kasugamycin-use strategies Designed to Delay Development of Resistance in Erwinia amylovora. Master thesis of Botany and Plant Pathology, Oregon state University.</p></span></p>

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