Notoginsenoside R1

  • CAT Number: I004930
  • CAS Number: 80418-24-2
  • Molecular Formula: C47H80O18
  • Molecular Weight: 933.13
  • Purity: ≥95%
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Notoginsenoside R1 (Cat.No:I004930) is a bioactive compound derived from the roots of Panax notoginseng, a traditional Chinese medicinal herb. Notoginsenoside R1 has been widely studied for its potential therapeutic effects, including anti-inflammatory, antioxidant, and cardioprotective properties. It shows promise in improving cardiovascular health, promoting neuroprotection, and modulating immune responses. Ongoing research explores its diverse pharmacological activities and potential clinical applications.

Catalog Number I004930
CAS Number 80418-24-2
Molecular Formula

C47H80O18

Purity 95%
Solubility 10 mM in DMSO
Storage 3 years -20℃ powder
IUPAC Name (2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
InChI InChI=1S/C47H80O18/c1-21(2)10-9-13-47(8,65-41-37(59)34(56)32(54)26(18-48)62-41)22-11-15-45(6)30(22)23(50)16-28-44(5)14-12-29(52)43(3,4)39(44)25(17-46(28,45)7)61-42-38(35(57)33(55)27(19-49)63-42)64-40-36(58)31(53)24(51)20-60-40/h10,22-42,48-59H,9,11-20H2,1-8H3/t22-,23+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36+,37+,38+,39-,40-,41-,42+,44+,45+,46+,47-/m0/s1
InChIKey LLPWNQMSUYAGQI-OOSPGMBYSA-N
SMILES CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(CO6)O)O)O)C)O)C)OC7C(C(C(C(O7)CO)O)O)O)C
Reference

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<br>[1]. Yang Y, et al. Notoginsenoside R1 reduces blood pressure in spontaneously hypertensive rats through a long non-coding RNA AK094457. Int J Clin Exp Pathol. 2015 Mar 1;8(3):2700-9.

<br>[2]. Li Zhi, et al. Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer&aposs; Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation. Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer&aposs; Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation, Volume 14, Number 3, April 2015, pp. 360-369(10)

<br>[3]. PU Xian-hong, et al. The Effect of Notoginsenoside R1 on TGF-β1/smad3 Signal Pathway in Hepatic Fibrosis Rats. Progress in Modern Biomedicine,
2015-04

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