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Nifuratel

Nifuratel

  • CAT Number: I003734
  • CAS Number: 4936-47-4
  • Molecular Formula: C10H11N3O5S
  • Molecular Weight: 285.28
  • Purity: ≥95%
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Nifuratel (Cat.No:I003734) is a synthetic nitrofuran derivative with antimicrobial properties. It is commonly used in the treatment of various vaginal and urinary tract infections, including bacterial vaginosis and trichomoniasis. Nifuratel exhibits broad-spectrum activity against bacteria, fungi, and protozoa, making it a versatile option in the management of infectious conditions.

Catalog Number I003734
CAS Number 4936-47-4
Synonyms

5-(methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one

Molecular Formula

C10H11N3O5S

Purity 95%
Target Antibiotic
Solubility 10 mM in DMSO
Storage Store at -20°C
IC50 0.125-1 μg/mL(MIC, A. vaginae) [1]
IUPAC Name 5-(methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
InChI InChI=1S/C10H11N3O5S/c1-19-6-8-5-12(10(14)18-8)11-4-7-2-3-9(17-7)13(15)16/h2-4,8H,5-6H2,1H3/b11-4+
InChIKey SRQKTCXJCCHINN-NYYWCZLTSA-N
SMILES CSCC1CN(C(=O)O1)N=CC2=CC=C(O2)[N+](=O)[O-]
Reference

<p style=/line-height:25px/>
<br>[1]. Polatti F. Bacterial vaginosis, Atopobium vaginae and nifuratel. Curr Clin Pharmacol. 2012 Feb 1;7(1):36-40.

<br>[2]. Nijevitch AA, et al. Helicobacter pylori eradication in childhood after failure of initial treatment: advantage of quadruple therapy withnifuratel to furazolidone. Aliment Pharmacol Ther. 2005 Nov 1;22(9):881-7.

<br>[3]. Nijevitch AA, et al. Nifuratel-containing initial anti-Helicobacter pylori triple therapy in children. Helicobacter. 2007 Apr;12(2):132-5.

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