N-Butanoyl-DL-homoserine lactone

• CAT Number: I017239
• CAS Number: 98426-48-3
• Molecular Formula: C₈H₁₃NO₃
• Molecular Weight: 171.19
• Purity: ≥95%
• Target: Bacterial
• IUPAC Name: N-(2-oxooxolan-3-yl)butanamide
• InChI: InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)
• InChIKey: VFFNZZXXTGXBOG-UHFFFAOYSA-N
• SMILES: CCCC(=O)NC1CCOC1=O

N-Butanoyl-DL-homoserine lactone (Cat No.:I017239) is a small signaling molecule belonging to the class of acyl-homoserine lactones (AHLs), commonly involved in bacterial quorum sensing. Quorum sensing is a process by which bacteria communicate to coordinate group behaviors based on population density, such as biofilm formation, virulence, and motility. N-Butanoyl-DL-homoserine lactone is produced by various Gram-negative bacteria and plays a critical role in regulating gene expression in response to environmental changes. This molecule’s study has implications in understanding bacterial infections and developing strategies to disrupt harmful bacterial communication pathways.

Reference

[1]. Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1[2]. Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19;14(2):e0212041.