CONTACT US
Home > Inhibitors/Agonists>AAK1> > LP-935509
LP-935509

LP-935509

  • CAT Number: I018161
  • CAS Number: 1454555-29-3
  • Molecular Formula: C₂₀H₂₄N₆O₃
  • Molecular Weight: 396.44
  • Purity: ≥95%
Inquiry Now

LP-935509 (Cat.No:I018161) is a selective, ATP-competitive and brain-penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1) with an IC50 and a Ki of 3.3 nM and 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure.

Catalog Number I018161
CAS Number 1454555-29-3
Molecular Formula

C₂₀H₂₄N₆O₃

Purity 95%
Reference

[1]. Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!