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Lomefloxacin

Lomefloxacin

  • CAT Number: I005723
  • CAS Number: 98079-51-7
  • Molecular Formula: C17H19F2N3O3
  • Molecular Weight: 351.35
  • Purity: ≥95%
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Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic.&nbsp;
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Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited.&nbsp;
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Catalog Number I005723
CAS Number 98079-51-7
Molecular Formula

C17H19F2N3O3

Purity 95%
Solubility 10mM in water (partly soluble)
Storage 3 years -20C powder
Reference

[1]. http://www.drugbank.ca/drugs/DB00978

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