For research use only. Not for therapeutic Use.
L48H37（Cat No.:I014797）is a small-molecule inhibitor that selectively targets the Wnt/β-catenin signaling pathway, a critical regulator of cell proliferation, differentiation, and stem cell renewal. By disrupting β-catenin–mediated transcriptional activity, L48H37 helps researchers study mechanisms underlying cancer progression, fibrosis, and developmental biology. It has been applied in oncology research to explore therapeutic strategies for Wnt-driven tumors and to dissect pathway regulation. L48H37 serves as a valuable tool compound in chemical biology, supporting investigations into signaling networks and advancing drug discovery focused on aberrant Wnt/β-catenin activity.
| CAS Number | 343307-76-6 |
| Synonyms | (3E,5E)-1-ethyl-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]piperidin-4-one |
| Molecular Formula | C27H33NO7 |
| Purity | ≥95% |
| IUPAC Name | (3E,5E)-1-ethyl-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]piperidin-4-one |
| InChI | InChI=1S/C27H33NO7/c1-8-28-15-19(9-17-11-21(30-2)26(34-6)22(12-17)31-3)25(29)20(16-28)10-18-13-23(32-4)27(35-7)24(14-18)33-5/h9-14H,8,15-16H2,1-7H3/b19-9+,20-10+ |
| InChIKey | IOFNKUXFKVPLPF-LQGKIZFRSA-N |
| SMILES | CCN1C/C(=C\C2=CC(=C(C(=C2)OC)OC)OC)/C(=O)/C(=C/C3=CC(=C(C(=C3)OC)OC)OC)/C1 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
