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Defactinib hydrochloride

Defactinib hydrochloride

  • CAT Number: I000338
  • CAS Number: 1073160-26-5
  • Molecular Formula: C20H22ClF3N8O3S
  • Molecular Weight: 546.95
  • Purity: ≥95%
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Defactinib hydrochloride(CAT: I000338) is a chemical compound that is also known as VS-6063 hydrochloride. It is an orally bioavailable small molecule inhibitor of the focal adhesion kinase (FAK). FAK is a protein kinase that plays a role in cell adhesion, migration, and survival. By inhibiting FAK, defactinib hydrochloride can potentially disrupt these cellular processes and inhibit tumor growth and metastasis. Defactinib hydrochloride has been investigated as a potential therapeutic agent in various cancers, including pancreatic cancer, ovarian cancer, and mesothelioma.

Catalog Number I000338
CAS Number 1073160-26-5
Molecular Formula

C20H22ClF3N8O3S

Purity 95%
Target FAK inhibitor
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

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<br>[1]. Kang Y, et al. Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. J Natl Cancer Inst. 2013 Oct 2;105(19):1485-95.

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