<span style="color:#000000;"><span style="font-size: 12px;"><font face="arial, helvetica, sans-serif">Ifenprodil Tartrate (CAS 23210-58-4) </font><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;"><font face="arial, helvetica, sans-serif">is an antagonist of NR1A/NR2B subunit-containing NMDA receptors (IC</font><font face="Lato, Lucida Grande, Lucida Sans Unicode, Lucida Sans, Geneva, Verdana, sans-serif">50</font></span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;"> = 340 nM).</span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;">Ifenprodil inhibits infection of MDCK cells by H1N1 and H3N2 influenza isolates in vitro</span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;"> (EC</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;"><font face="Lato, Lucida Grande, Lucida Sans Unicode, Lucida Sans, Geneva, Verdana, sans-serif">50</font></span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;">s = 7.2 and 12.1 µM, respectively).</span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;"> It increases the production of NGF, BDNF, and GDNF in primary mouse astrocytes when used at a concentration of 150 µM.</span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;"> Ifenprodil also reduces maximal electroshock seizures in mice (ED</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;"><font face="Lato, Lucida Grande, Lucida Sans Unicode, Lucida Sans, Geneva, Verdana, sans-serif">50</font></span><span style="font-family: arial, helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;">s = 16 and 7 mg/kg, respectively).</span></span></span>