Herbimycin A

• CAT Number: I010434
• CAS Number: 70563-58-5
• Molecular Formula: C₃₀H₄₂N₂O₉
• Molecular Weight: 574.7
• Purity: ≥95%
• Target: Src
• Solubility: Soluble to 10 mM in DMSO
• Storage: Store at -20C
• InChI: InChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9+,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0
• InChIKey: MCAHMSDENAOJFZ-GDYSMBPZSA-N
• SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)OC)OC

Herbimycin A (Cat.No:I010434) is a natural antibiotic and protein tyrosine kinase inhibitor. It has been studied for its potential anticancer and antiviral activities. Herbimycin A selectively binds to the ATP-binding site of tyrosine kinases, disrupting their function and inhibiting cell growth. It is a valuable tool in research and drug development targeting protein kinases.

Reference

Eichhorn, Kai. /Geldanamycin: The Prototype of a Class of Antitumor Drugs Targeting the Heat Shock Protein 90 Family of Molecular Chaperones./ Cell Stress Chaperones6.2 (2001): 105-12. www.ncbi.gov. Web. 6 Sept. 2012.