Glimepiride - CAS 93479-97-1

Glimepiride (CAT: I005553) is an oral medication belonging to the class of sulfonylurea drugs used for the management of type 2 diabetes mellitus. It works by stimulating the release of insulin from pancreatic beta cells and improving insulin sensitivity in peripheral tissues, thereby helping to lower blood glucose levels. Glimepiride is typically prescribed along with diet and exercise to control blood sugar levels in individuals with diabetes. It is important to follow the prescribed dosage and instructions provided by a healthcare professional when using glimepiride.

Catalog Number: I005553

CAS Number: 93479-97-1

PubChem Substance ID:355170365

Molecular Formula: C24H34N4O5S

Molecular Weight:490.619

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide

Property

Molecular Formula: C24H34N4O5S
Molecular Weight490.619
Target:DPP-4
SolubilityDMSO 11 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL
Purity≥95%
Storage3 years -20C powder
Overview of Clinical Research<span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>Glimepiride is a potassium channel agonist.&nbsp;Sanofi completed the phase III RECOMMEND trial in Type-2 diabetes mellitus (combination therapy) in Algeria, Colombia, Egypt, Guatemala, India, Iran, Lebanon, Mexico, Russia, Saudi Arabia, South Africa, Tunisia, Turkey, Ukraine and the United Arab Emirates (NCT01459809) in 2014.</span></span></span>

Computed Descriptor

IUPAC Name4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
InChIInChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)
InChIKeyWIGIZIANZCJQQY-UHFFFAOYSA-N
SMILESCCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C