Quinidine

  • CAT Number: R007506
  • CAS Number: 56-54-2
  • Molecular Formula: C20H24N2O2
  • Molecular Weight: 324.42
  • Purity: ≥95%
Inquiry Now

Quinidine is a dextrorotatory stereoisomer of quinine with antimalarial and antiarrhythmic properties.

Catalog Number R007506
CAS Number 56-54-2
Synonyms

(9S)-6’-Methoxycinchonan-9-ol; (+)-Quinidine; (8R,9S)-Quinidine; Chinidin; Cin-quin; Conchinin; Conchinine; Conquinine; Kinidin; Pitayin; Pitayine; Quindine; β-Quinidine; β-Quinine;

Molecular Formula

C20H24N2O2

Purity 95%
Target Other Channel Modulators
Solubility >12mg/mL in DMSO
Storage Store at -20C
Reference

</br>1:Quinidine for Brugada syndrome: Panacea or poison? Hai JJ, Wong CK, Chan PH, Tse HF, Yung TC, Siu CW.HeartRhythm Case Rep. 2016 Aug 16;2(6):486-490. doi: 10.1016/j.hrcr.2016.07.002. eCollection 2016 Nov. No abstract available. PMID: 28491743 Free PMC Article</br>2:Dextromethorphan/quinidine pharmacotherapy in patients with treatment resistant depression: A proof of concept clinical trial. Murrough JW, Wade E, Sayed S, Ahle G, Kiraly DD, Welch A, Collins KA, Soleimani L, Iosifescu DV, Charney DS.J Affect Disord. 2017 Apr 29;218:277-283. doi: 10.1016/j.jad.2017.04.072. [Epub ahead of print] PMID: 28478356 </br>3:Assessing the clinical efficacy of quinidine in Brugada syndrome: /Mission: Impossible/? Belhassen B.Heart Rhythm. 2017 Apr 26. pii: S1547-5271(17)30501-5. doi: 10.1016/j.hrthm.2017.04.034. [Epub ahead of print] No abstract available. PMID: 28455270 </br>4:Liquid and subcritical fluid chromatographic enantioseparation of N<sup>α</sup> -Fmoc proteinogenic amino acids on Quinidine-based zwitterionic and anion-exchanger type chiral stationary phases. A comparative study. Lajkó G, Grecsó N, Tóth G, Fülöp F, Lindner W, Ilisz I, Péter A.Chirality. 2017 Apr 19. doi: 10.1002/chir.22700. [Epub ahead of print] PMID: 28422383 </br>5:Antitachycardia Pacing Effectiveness for Monomorphic Ventricular Tachycardia in Brugada Syndrome After Quinidine Administration. Dallaglio PD, Anguera I, García-Alberola A, Sabaté X, Cequier Á, Brugada J.Rev Esp Cardiol (Engl Ed). 2017 Mar 31. pii: S1885-5857(17)30121-4. doi: 10.1016/j.rec.2017.03.002. [Epub ahead of print] English, Spanish. No abstract available. PMID: 28372913 </br>6:Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson/’s disease. Fox SH, Metman LV, Nutt JG, Brodsky M, Factor SA, Lang AE, Pope LE, Knowles N, Siffert J.Mov Disord. 2017 Mar 30. doi: 10.1002/mds.26976. [Epub ahead of print] PMID: 28370447 </br>7:Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP<sub>2</sub>-interference. Koepple C, Scherer D, Seyler C, Scholz E, Thomas D, Katus HA, Zitron E.J Pharmacol Exp Ther. 2017 May;361(2):209-218. doi: 10.1124/jpet.116.238287. Epub 2017 Feb 10. PMID: 28188270 </br>8:Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study. Bilonda MK, Mammino L.Molecules. 2017 Feb 7;22(2). pii: E245. doi: 10.3390/molecules22020245. PMID: 28178218 Free Article</br>9:Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA. Giri P, Delvadia P, Gupta L, Patel N, Trivedi P, Lad K, Patel HM, Srinivas NR.Xenobiotica. 2017 Jan 19:1-10. doi: 10.1080/00498254.2016.1275064. [Epub ahead of print] PMID: 28010169 </br>10:Use of Compounded Dextromethorphan-Quinidine Suspension for Pseudobulbar Affect in Hospice Patients. Wahler RG Jr, Reiman AT, Schrader JV.J Palliat Med. 2017 Mar;20(3):294-297. doi: 10.1089/jpm.2016.0277. Epub 2016 Dec 20. PMID: 27997281

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!