Furagin

• CAT Number: I002186
• CAS Number: 1672-88-4
• Molecular Formula: C10H8N4O5
• Molecular Weight: 264.19
• Purity: ≥95%
• Target: Antibiotic
• Solubility: DMSO:33mg/mL
• Storage: Store at -20°C
• IUPAC Name: 1-[(E)-[(E)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione
• InChI: InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
• InChIKey: DECBQELQORZLLP-UAIOPKHMSA-N
• SMILES: C1C(=O)NC(=O)N1N=CC=CC2=CC=C(O2)[N+](=O)[O-]

Furagin（Cat No.:I002186） is an antibacterial agent that belongs to the nitrofurantoin analog class. It is a 2-substituted 5-nitrofuran compound that shares a similar chemical and structural profile with nitrofurantoin, a widely used antibacterial compound. Furagin exhibits antimicrobial activity against various bacterial pathogens. It works by inhibiting the growth and replication of bacteria, making it effective in the treatment of bacterial infections.

Reference

1:Ciprofloxacin and furagin in acute cystitis: comparison of early immune and microbiological results. Dybowski B, Jabłońska O, Radziszewski P, Gromadzka-Ostrowska J, Borkowski A.Int J Antimicrob Agents. 2008 Feb;31(2):130-4. Epub 2007 Dec 3. PMID: 18060746 2:Cytogenetic analysis of children under long-term antibacterial therapy with nitroheterocyclic compound furagin. Slapsyte G, Jankauskiene A, Mierauskiene J, Lazutka JR.Mutat Res. 2001 Apr 5;491(1-2):25-30. PMID: 11287294 3:[Pulmonary reaction after furazidin (Furagin). Case report]. Zielonka TM, Demkow U, Kuś J.Pol Arch Med Wewn. 1997 May;97(5):465-72. Polish. PMID: 9411425 4:[Photosensitizing properties and antioxidant activity of furagin–an antimicrobial drug that is a derivative of nitrofuran]. Makareeva EN, Lozovskaia EL, Tatikolov AS, Sapezhinskiĭ II.Biofizika. 1997 Mar-Apr;42(2):472-9. Russian. PMID: 9172693 5:[Action of furagin, nystatin and levorin with bile acids on the vaginal microflora of pregnant women]. Kuchuma ZN.Vrach Delo. 1986 Oct;(10):10-3. Russian. No abstract available. PMID: 3798871 6:[Combined effect of benzylpenicillin, furagin and bile acids on staphylococci]. Sytnik IA, Tkachuk NI.Antibiotiki. 1982 Nov;27(11):823-7. Russian. PMID: 7181465 7:[Aspects of urinary furagin excretion in rabbits]. Paberza MIa, Gilev AP, Parinov VIa.Farmatsiia. 1980 May-Jun;29(3):66-7. Russian. No abstract available. PMID: 7409226 8:[Express acidimetric method of determining soluble furagin]. Suprun PP.Farm Zh. 1980;(1):71-2. Ukrainian. No abstract available. PMID: 7371820 9:Pharmacokinetics of furagin, a new nitrofurantoin congener, on human volunteers. Männistö P, Karttunen P.Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):264-70. PMID: 468451 10:[Use of furagin in treatment of urinary tract infections]. Mis M, Boian M, Lente I, Shari B, Boda Z.Ter Arkh. 1978;50(2):119-23. Russian. No abstract available. PMID: 25493