Donepezil HCl

  • CAT Number: A000207
  • CAS Number: 120011-70-3
  • Molecular Formula: C24H30ClNO3
  • Molecular Weight: 415.95
  • Purity: ≥95%
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Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.<br>Donepezil inhibits the carbachol-stimulated increase in intracellular Ca<br>Intraperitoneal administration of Donepezil in rats produces a dose dependent increase in salivation and tremor, which are overt cholinergic behavioural signs, with an ED50 of 6 μmol/kg. Donepezil is found to be somewhat less potent with a ED50 of 50 μmol/kg following oral administration.

Catalog Number A000207
CAS Number 120011-70-3
Synonyms

NA

Molecular Formula

C24H30ClNO3

Purity 95%
Target Histone Acetyltransferases
Solubility Limited solubility
Storage 3 years -20C powder

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