Decarbamoylsaxitoxin

• CAT Number: T000006
• CAS Number: 58911-04-9
• Molecular Formula: C9H16N6O3
• Molecular Weight: 256.266
• Purity: ≥95%
• Synonyms: Decarbamoylsaxitoxin; Decarbamylsaxitoxin; Descarbamoylsaxitoxin
• Storage: -20°C
• IUPAC Name: (3aS,4R,10aS)-2,6-diamino-4-(hydroxymethyl)-3a,4,8,9-tetrahydro-3H-pyrrolo[1,2-c]purine-10,10-diol
• InChI: InChI=1S/C9H16N6O3/c10-6-13-5-4(3-16)12-7(11)15-2-1-8(17,18)9(5,15)14-6/h4-5,16-18H,1-3H2,(H2,11,12)(H3,10,13,14)/t4-,5-,9-/m0/s1
• InChIKey: VRRIYZJUSNMZMP-PJPYAQQDSA-N
• SMILES: C1CN2C(=NC(C3C2(C1(O)O)N=C(N3)N)CO)N

Decarbamoylsaxitoxin (CAS 58911-04-9), abbreviated as dcSTX, is a neurotoxin which is naturally produced in dinoflagellate. DcSTX is one of the many analogues of saxitoxin. Saxitoxin is a tricyclic alkaloid compound, which has multiple structural related neurotoxins.

Reference

1.Jellett, J. F., J. E. Stewart, and M. V. Laycock. "Toxicological evaluation of saxitoxin, neosaxitoxin, gonyautoxin II, gonyautoxin II plus III and decarbamoylsaxitoxin with the mouse neuroblastoma cell bioassay." Toxicology in vitro 9.1 (1995): 57-65.
2.Koehn, F. E., H. K. Schnoes, and C. Y. Kao. "On the structure and biological properties of decarbamoylsaxitoxin." Biochimica et Biophysica Acta (BBA)-Biomembranes 734.2 (1983): 129-132.
3.Koehn, Frank E., et al. "Derivatives of saxitoxin." Bioorganic Chemistry 10.4 (1981): 412-428.