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Dapoxetine HCl

Dapoxetine HCl

  • CAT Number: A001071
  • CAS Number: 129938-20-1
  • Molecular Formula: C21H23NO • HCl
  • Molecular Weight: 341.9
  • Purity: ≥95%
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Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.<br>Dapoxetine not only reduces the peak amplitude of Kv4.3 currents but also accelerates the decay rate of current inactivation in a concentration-dependent manner. Dapoxetine decreases the integral of the Kv4.3 currents over the duration of a depolarizing pulse with an IC50 of 5.3 μM. Dapoxetine also causes a substantial acceleration in closed-state inactivation. Dapoxetine produces a significant use-dependent block, which is accompanied by a delayed recovery from inactivation of Kv4.3 currents.

Catalog Number A001071
CAS Number 129938-20-1
Molecular Formula

C21H23NO • HCl

Purity 95%
Target 5-HT Receptor
Solubility Soluble in DMSO > 10 mM
Storage 3 years -20C powder
InChIKey IHWDIQRWYNMKFM-BDQAORGHSA-N

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