Metformin is a common first line antidiabetic drug, and the only FDA approved member of the biguanide drug class. More recently it has drawn attention from the cancer research sector. Several clinical trials for the use of metformin in the treatment of cancer have been performed.</br>Researchers have not yet decided on the precise anti-cancer mechanism of action for Metformin.
| Catalog Number | A000376 |
| CAS Number | 1115-70-4 |
| Synonyms | NA |
| Molecular Formula | C4H11N5 • HCl |
| Purity | 95% |
| Target | AMPK |
| Storage | 3 years -20C powder |
| InChIKey | OETHQSJEHLVLGH-UHFFFAOYSA-N |
| Reference | Kourelis, T. V., & Siegel, R. D. (2011). Metformin and cancer: New applications for an old drug. Medical Oncology, 29(2), 1314–1327. doi:10.1007/s12032-011-9846-7<br/><br/>Pawlyk AC, Giacomini KM, McKeon C, Shuldiner AR, Florez JC. Metformin Pharmacogenomics: Current Status and Future Directions. Diabetes. 2014;63(8):2590-2599. doi:10.2337/db13-1367.</span></p> |
