Chlorhexidine

• CAT Number: I004070
• CAS Number: 55-56-1
• Molecular Formula: C22H30Cl2N10
• Molecular Weight: 505.446
• Purity: ≥95%
• Target: Antibacterial
• Solubility: DMSO: ≥ 31 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
• InChI: InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
• InChIKey: GHXZTYHSJHQHIJ-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl

Chlorhexidine (CAT: I004070) is an antiseptic and disinfectant commonly used in various healthcare settings. It has broad-spectrum activity against bacteria, fungi, and some viruses. Chlorhexidine is often used to clean and disinfect the skin before surgical procedures, as well as to sanitize hands in healthcare settings. It is also used in oral care products, such as mouthwashes and toothpaste, to prevent dental plaque and gingivitis. Chlorhexidine works by disrupting the cell membranes of microorganisms, leading to their death or inhibition of growth. It is generally well-tolerated, but some individuals may experience temporary discoloration of the teeth or oral mucosa with long-term use.

Overview of Clinical Research

Chlorhexidine is a cell wall modulator. It has not been granted for the orphan drug status.

Reference

1.Moshrefi, Abdy. "Chlorhexidine." The Journal of the Western Society of Periodontology/periodontal Abstracts. Vol. 50. No. 1. 2002.
2.Russell, A. D., and M. J. Day. "Antibacterial activity of chlorhexidine." Journal of Hospital Infection 25.4 (1993): 229-238.
3.Hugo, W. B., and A. R. Longworth. "Some aspects of the mode of action of chlorhexidine." Journal of Pharmacy and Pharmacology 16.10 (1964): 655-662.