For research use only. Not for therapeutic Use.
CGP 12177 Hydrochloride(CAT: I010374) is a potent, non-selective β-adrenergic receptor ligand that acts as a partial agonist or antagonist depending on receptor subtype and tissue context. It primarily targets β₁- and β₂-adrenergic receptors and has been widely used in cardiovascular and receptor pharmacology research to study adrenergic signaling, receptor desensitization, and β-adrenergic function in the heart and lungs. CGP 12177 also serves as a valuable tool for characterizing atypical β-adrenergic binding sites. Supplied as a hydrochloride salt for enhanced solubility and stability.
| CAS Number | 64208-32-8 |
| Synonyms | 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one;hydrochloride |
| Molecular Formula | C14H22ClN3O3 |
| Purity | ≥95% |
| IUPAC Name | 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one;hydrochloride |
| InChI | InChI=1S/C14H21N3O3.ClH/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10;/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19);1H |
| InChIKey | YQVFCYCTITZLSX-UHFFFAOYSA-N |
| SMILES | CC(C)(C)NCC(COC1=CC=CC2=C1NC(=O)N2)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
