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YH-306

YH-306

  • CAT Number: I038545
  • CAS Number: 1373764-75-0
  • Molecular Formula: C19H18N2O2
  • Molecular Weight: 306.36
  • Purity: 98%
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YH-306（Cat No.:I038545） is a compound that functions as a modulator of the FAK (focal adhesion kinase) signaling pathway. Its mechanism of action involves suppressing the growth and metastasis of colorectal tumors. By targeting the FAK signaling pathway, YH-306 exhibits potential as a therapeutic agent for the treatment of colorectal cancer.

Catalog Number I038545
CAS Number 1373764-75-0
Molecular Formula

C19H18N2O2

Purity 98
Solubility Soluble in DMSO
Storage 4°C, protect from light
IUPAC Name 2-(4-Hydroxyphenyl)-1-(1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-ethanone
InChI InChI=1S/C19H18N2O2/c22-14-7-5-13(6-8-14)11-19(23)21-10-9-16-15-3-1-2-4-17(15)20-18(16)12-21/h1-8,20,22H,9-12H2
InChIKey WFTJZQLEQGPZBC-UHFFFAOYSA-N
SMILES OC1=CC=C(CC(N(C2)CCC3=C2NC4=C3C=CC=C4)=O)C=C1
Reference

1: Dai F, Chen Y, Huang L, Wang J, Zhang T, Li J, Tong W, Liu M, Yi Z. A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. J Cell Mol Med. 2015 Feb;19(2):383-95. doi: 10.1111/jcmm.12450. Epub 2014 Oct 29. PubMed PMID: 25351103; PubMed Central PMCID: PMC4407606.

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