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Cefuroxime Acid

Cefuroxime Acid

  • CAT Number: M013100
  • CAS Number: 55268-75-2
  • Molecular Formula: C16H16N4O8S
  • Molecular Weight: 424.39
  • Purity: ≥95%
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Cefuroxime Acid (Cat.No:M013100) is the active metabolite of the antibiotic cefuroxime. It belongs to the class of cephalosporin antibiotics and is used to treat various bacterial infections. Cefuroxime Acid works by interfering with bacterial cell wall synthesis, leading to bacterial cell death. It is available in oral and injectable formulations for clinical use.

Catalog Number M013100
CAS Number 55268-75-2
Molecular Formula

C16H16N4O8S

Purity 95%
Storage Room temperature
InChIKey JFPVXVDWJQMJEE-SWWZKJRFSA-N
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Reference

1: Bertholee D, ter Horst PG, Hijmering ML, Spanjersberg AJ, Hospes W, Wilffert
B. Blood concentrations of cefuroxime in cardiopulmonary bypass surgery. Int J
Clin Pharm. 2013 Oct;35(5):798-804. doi: 10.1007/s11096-013-9810-z. Epub 2013 Jun
21. PubMed PMID: 23794078.
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2: Christiansen IS, Kr&#248;igaard M, Mosbech H, Skov PS, Poulsen LK, Garvey LH.
Clinical and diagnostic features of perioperative hypersensitivity to cefuroxime.
Clin Exp Allergy. 2015 Apr;45(4):807-14. doi: 10.1111/cea.12455. PubMed PMID:
25395022.

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3: Promelle V, Jany B, Drimbea A, Jezraoui P, Milazzo S. Tolerability of
intracameral cefuroxime during cataract surgery in case of penicillin allergy. J
Fr Ophtalmol. 2015 Apr;38(4):283-7. doi: 10.1016/j.jfo.2014.11.005. Epub 2015 Apr
1. PubMed PMID: 25840617.
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4: Kulapina OI, Mikhailova MS. [Study on pharmacokinetics of cefuroxime by
dynamics of its distribution in oral fluid of patients with sinusitis]. Antibiot
Khimioter. 2014;59(9-10):29-32. Russian. PubMed PMID: 25975113.

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5: Bookstaver DA, Bland CM, Woodberry MW, Mansell KB. Correlation of cefpodoxime
susceptibility with cephalothin and cefuroxime for urinary tract isolates. J Med
Microbiol. 2014 Feb;63(Pt 2):218-21. doi: 10.1099/jmm.0.063040-0. Epub 2013 Nov
8. PubMed PMID: 24214230.

<br>
6: Myneni J, Desai SP, Jayamanne DG. Reduction in postoperative endophthalmitis
with intracameral cefuroxime. J Hosp Infect. 2013 Aug;84(4):326-8. doi:
10.1016/j.jhin.2013.05.009. Epub 2013 Jul 5. PubMed PMID: 23834989.

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7: Rodríguez-Caravaca G, García-Sáenz MC, Villar-Del-Campo MC, Andrés-Alba Y,
Arias-Puente A. Incidence of endophthalmitis and impact of prophylaxis with
cefuroxime on cataract surgery. J Cataract Refract Surg. 2013 Sep;39(9):1399-403.
doi: 10.1016/j.jcrs.2013.03.031. Epub 2013 Jun 29. PubMed PMID: 23820306.

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