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Capreomycin

Capreomycin

  • CAT Number: M058916
  • CAS Number: 11003-38-6
  • Molecular Formula: C25H44N14O7 (for IB)
  • Purity: 98%
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Capreomycin(cas 11003-38-6) is a complex of cyclic pentopeptides isolated from Streptomyces capreolus, first reported in 1962. The complex has two major components, IA and IB, with an exocyclic lysine residue and two minor delysinyl components, IIA and IIB. Capreomycin is a potent antibiotic with activity against mycobateria, Gram positive and Gram negative organisms. Capreomycin acts by binding to the 23S ribosomal subunit, disrupting protein synthesis.

Catalog Number M058916
CAS Number 11003-38-6
Molecular Formula

C25H44N14O7 (for IB)

Purity 98
Storage -80°C
Analysis method HPLC
Reference

Chemical and biological properties of capreomycin and other peptide antibiotics. Herr E.B. Antimicrob. Agents Chemother. 1962, 1963, 201.<br />
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Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin. Akbergenov R. et al. Antimicrob. Agents Chemother. 2011, 55, 4712.
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