Brilacidin Tetrahydrochloride

• CAT Number: R014401
• CAS Number: 1224095-99-1
• Molecular Formula: C40H54Cl4F6N14O6
• Molecular Weight: 1082.754
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 4-N,6-N-bis[3-[5-(diaminomethylideneamino)pentanoylamino]-2-[(3R)-pyrrolidin-3-yl]oxy-5-(trifluoromethyl)phenyl]pyrimidine-4,6-dicarboxamide;tetrahydrochloride
• InChI: InChI=1S/C40H50F6N14O6.4ClH/c41-39(42,43)21-13-25(57-31(61)5-1-3-9-53-37(47)48)33(65-23-7-11-51-18-23)27(15-21)59-35(63)29-17-30(56-20-55-29)36(64)60-28-16-22(40(44,45)46)14-26(34(28)66-24-8-12-52-19-24)58-32(62)6-2-4-10-54-38(49)50;;;;/h13-17,20,23-24,51-52H,1-12,18-19H2,(H,57,61)(H,58,62)(H,59,63)(H,60,64)(H4,47,48,53)(H4,49,50,54);4*1H/t23-,24-;;;;/m1..../s1
• InChIKey: QTHBCQCKYVOFDR-PIJQHSLXSA-N
• SMILES: C1CNCC1OC2=C(C=C(C=C2NC(=O)CCCCN=C(N)N)C(F)(F)F)NC(=O)C3=CC(=NC=N3)C(=O)NC4=C(C(=CC(=C4)C(F)(F)F)NC(=O)CCCCN=C(N)N)OC5CCNC5.Cl.Cl.Cl.Cl

Brilacidin Tetrahydrochloride (Cat.No:R014401) is a synthetic antimicrobial peptide with broad-spectrum activity against bacteria, viruses, and fungi. It has demonstrated potential in treating various infections, including skin and soft tissue infections, oral mucositis, and COVID-19. Brilacidin’s unique mechanism of action and low likelihood of resistance make it a promising candidate for novel therapeutic approaches.