Aripiprazole

  • CAT Number: A000519
  • CAS Number: 129722-12-9
  • Molecular Formula: C₂₃H₂₇Cl₂N₃O₂
  • Molecular Weight: 448.4
  • Purity: ≥95%
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Aripiprazole (Cat No.:A000519) is a new highly lipid-soluble quinolone derivative. As a new atypical antipsychotic drug, it has the advantages of low side effects, significant efficacy and low relapse rate, and is suitable for the long-term treatment of schizophrenic patients throughout the course of their illness.

Catalog Number A000519
CAS Number 129722-12-9
Molecular Formula

C₂₃H₂₇Cl₂N₃O₂

Purity 95%
Target Dopamine Receptor
Solubility Soluble in DMSO > 10 mM
Storage -20°C
InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
InChIKey CEUORZQYGODEFX-UHFFFAOYSA-N
SMILES C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
Reference

1: She S, Kuang Q, Zheng Y. Aripiprazole-induced tardive dyskinesia in patients
with schizophrenia: A case report of twins. Schizophr Res. 2017 Nov 8. pii:
S0920-9964(17)30664-3. doi: 10.1016/j.schres.2017.10.036. [Epub ahead of print]
PubMed PMID: 29128325.
<br>

2: Reddy B, Ali M, Guruprasad S, Das S. Hypersexuality induced by Aripiprazole:
Two case reports and review of the literature. Asian J Psychiatr. 2017 Oct 25.
pii: S1876-2018(17)30692-5. doi: 10.1016/j.ajp.2017.10.008. [Epub ahead of print]
PubMed PMID: 29107566.
<br>

3: Scheggi S, Pelliccia T, Gambarana C, De Montis MG. Aripiprazole relieves
motivational anhedonia in rats. J Affect Disord. 2017 Oct 20;227:192-197. doi:
10.1016/j.jad.2017.10.032. [Epub ahead of print] PubMed PMID: 29100151.
<br>

4: Kopelowicz A, Baker RA, Zhao C, Brewer C, Lawson E, Peters-Strickland T. A
multicenter, open-label, pilot study evaluating the functionality of an
integrated call center for a digital medicine system to optimize monitoring of
adherence to oral aripiprazole in adult patients with serious mental illness.
Neuropsychiatr Dis Treat. 2017 Oct 19;13:2641-2651. doi: 10.2147/NDT.S143091.
eCollection 2017. PubMed PMID: 29089771; PubMed Central PMCID: PMC5656350.
<br>

5: Vázquez-Bourgon J, Pérez-Iglesias R, Ortiz-García de la Foz V, Suárez Pinilla
P, Díaz Martínez á, Crespo-Facorro B. Long-term metabolic effects of
aripiprazole, ziprasidone and quetiapine: a pragmatic clinical trial in
drug-na&#239;ve patients with a first-episode of non-affective psychosis.
Psychopharmacology (Berl). 2017 Oct 26. doi: 10.1007/s00213-017-4763-x. [Epub
ahead of print] PubMed PMID: 29075885.
<br>

6: Kutuk MO, Guler G, Tufan AE, Kutuk O. Hiccup Due to Aripiprazole Plus
Methylphenidate Treatment in an Adolescent with Attention Deficit and
Hyperactivity Disorder and Conduct Disorder: A Case Report. Clin Psychopharmacol
Neurosci. 2017 Nov 30;15(4):410-412. doi: 10.9758/cpn.2017.15.4.410. PubMed PMID:
29073754.
<br>

7: Hudson R, Zhou Y, Leri F. The combination of escitalopram and aripiprazole:
Investigation of psychomotor effects in rats. J Psychopharmacol. 2017 Oct
1:269881117732515. doi: 10.1177/0269881117732515. [Epub ahead of print] PubMed
PMID: 29069975.

<br>
8: Das S, Chatterjee SS, Bagewadi V. Aripiprazole induced hypersexuality, when we
should be cautious? Asian J Psychiatr. 2017 Oct;29:162-163. doi:
10.1016/j.ajp.2017.05.023. Epub 2017 Jun 8. PubMed PMID: 29061419.
<br>

9: Britnell SR, Jackson AD, Brown JN, Capehart BP. Aripiprazole for
Post-traumatic Stress Disorder: A Systematic Review. Clin Neuropharmacol. 2017
Nov/Dec;40(6):273-278. doi: 10.1097/WNF.0000000000000251. PubMed PMID: 29059134.
<br>

10: De Berardis D, Olivieri L, Nappi F, Rapini G, Vellante F, Matarazzo I,
Serroni N, Di Giannantonio M. Vortioxetine and Aripiprazole Combination in
Treatment-Resistant Obsessive-Compulsive Disorder: A Case Report. J Clin
Psychopharmacol. 2017 Dec;37(6):732-734. doi: 10.1097/JCP.0000000000000801.
PubMed PMID: 29040153.

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