Irbesartan - CAS 138402-11-6

Irbesartan (INN) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.

Catalog Number: A000217

CAS Number: 138402-11-6

PubChem Substance ID:355038848

Molecular Formula: C25H28N6O

Molecular Weight:428.5

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms138402-11-6; Aprovel; Avapro; Karvea; SR-47436

Property

Molecular Formula: C25H28N6O
Molecular Weight428.5
Target:Angiotensin Receptor
Solubility>17.4mg/mL in DMSO
Purity≥95%
Storage-20°C

Computed Descriptor

InChI1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
InChIKeyYOSHYTLCDANDAN-UHFFFAOYSA-N
SMILESCCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5