1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE


CAS No. : 18851-33-7

1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE,18851-33-7
Product Details
Cat No:M084057
Molecular Formula:C12H11ClN2O
Molecular Weight:234.683
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Appearance:White to off-white powder
Water Content (Karl Fisher):Not more than 8.5%
Cat No:M084057
Cas No:18851-33-7
Product-Name:1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
IUPAC Name:1,10-phenanthroline;hydrate;hydrochloride
InChI:InChI=1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2
InChIKey:NDLHUHRGAIHALB-UHFFFAOYSA-N
SMILES:C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O.Cl
1,10-phenanthroline hydrochloride monohydrate is a herterocyclic compound with antimycotic and anticancer properties.
1,10-phenanthroline HCl monohydrate damages mitochondrial function in fungi by disabling the ability to reduce 2,3,5-triphenyltetrazolium chloride (TTC). 1,10-phenanthroline also inhibits DNA synthesis in cancer cells; however, the mechanism is poorly understood.
Deegan, Carol. /In Vitro Cancer Chemotherapeutic Activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)] · 2H2O, [Cu(phen)2(mal)] · 2H2O and [Mn(phen)2(mal)] · 2H2O (malH2 = Malonic Acid) Using Human Cancer Cells./ Cancer Letters 247.2 (2007): 224-33. Web.

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