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1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE

1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE

  • CAT Number: M084057
  • CAS Number: 18851-33-7
  • Molecular Formula: C12H11ClN2O
  • Molecular Weight: 234.683
  • Purity: ≥95%
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1,10-phenanthroline hydrochloride monohydrate is a herterocyclic compound with antimycotic and anticancer properties.</br>1,10-phenanthroline HCl monohydrate damages mitochondrial function in fungi by disabling the ability to reduce 2,3,5-triphenyltetrazolium chloride (TTC). 1,10-phenanthroline also inhibits DNA synthesis in cancer cells; however, the mechanism is poorly understood.

Catalog Number M084057
CAS Number 18851-33-7
Molecular Formula

C12H11ClN2O

Purity 95%
Storage Desiccate at RT
IUPAC Name 1,10-phenanthroline;hydrate;hydrochloride
InChI InChI=1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2
InChIKey NDLHUHRGAIHALB-UHFFFAOYSA-N
SMILES C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O.Cl
Reference

Deegan, Carol. /In Vitro Cancer Chemotherapeutic Activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)] · 2H2O, [Cu(phen)2(mal)] · 2H2O and [Mn(phen)2(mal)] · 2H2O (malH2 = Malonic Acid) Using Human Cancer Cells./ Cancer Letters 247.2 (2007): 224-33. Web.<br/><br/>

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