6''-O-Acetylsaikosaponin A

• CAT Number: I044904
• CAS Number: 64340-46-1
• Molecular Formula: C44H70O14
• Molecular Weight: 823.02
• Purity: ≥95%
• Synonyms: [(2R,3S,4S,5R,6S)-6-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-[[(1S,2S,4S,5R,8R,9R,10S,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate
• InChI: InChI=1S/C44H70O14/c1-22-30(48)35(58-36-33(51)32(50)31(49)24(56-36)19-53-23(2)46)34(52)37(55-22)57-29-11-12-39(5)25(40(29,6)20-45)9-13-41(7)26(39)10-14-44-27-17-38(3,4)15-16-43(27,21-54-44)28(47)18-42(41,44)8/h10,14,22,24-37,45,47-52H,9,11-13,15-21H2,1-8H3/t22-,24-,25-,26-,27-,28+,29+,30+,31-,32+,33-,34-,35+,36+,37+,39+,40+,41-,42+,43-,44+/m1/s1
• InChIKey: WDWZBAMDKXKRBA-HCYXLWPCSA-N
• SMILES: C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]2CC[C@]3([C@H]([C@]2(C)CO)CC[C@@]4([C@@H]3C=C[C@@]56[C@]4(C[C@@H]([C@@]7([C@H]5CC(CC7)(C)C)CO6)O)C)C)C)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)COC(=O)C)O)O)O)O

6”-O-Acetylsaikosaponin A（Cat No.:I044904）is a bioactive oleanane-type triterpenoid saponin derived from Bupleurum species, particularly Bupleurum chinense, a key herb in traditional Chinese medicine. This acetylated saikosaponin exhibits enhanced pharmacological effects, including anti-inflammatory, hepatoprotective, and immunomodulatory activities. It acts on pathways such as NF-κB and MAPK, reducing pro-inflammatory cytokine production and protecting liver cells from damage. The acetyl group at the 6”-position of the sugar moiety is believed to improve membrane permeability and bioavailability. 6”-O-Acetylsaikosaponin A is a promising candidate for treating liver diseases and inflammatory disorders.