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Camicinal free base

Camicinal free base

  • CAT Number: I005448
  • CAS Number: 923565-21-3 (free base)
  • Molecular Formula: C25H33FN4O
  • Molecular Weight: 424.5644
  • Purity: ≥95%
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Camicinal, also known as GSK962040, is a selective motilin receptor agonist and effective as a stimulant of human and rabbit gastrointestinal motility. Camicinal represents a new opportunity as a treatment in a clinical area in need of new agents.

Catalog Number I005448
CAS Number 923565-21-3 (free base)
Synonyms

GSK962040; GSK-962040; GSK 962040; Camicinal.;(S)-1-(4-((3-fluorophenyl)amino)piperidin-1-yl)-2-(4-((3-methylpiperazin-1-yl)methyl)phenyl)ethan-1-one

Molecular Formula

C25H33FN4O

Purity 95%
Target motilin receptor agonist
Solubility Soluble in DMSO, not in water
Storage 0 - 4°C for short term ,or -20 °C for long term
InChI InChI=1S/C25H33FN4O/c1-19-17-29(14-11-27-19)18-21-7-5-20(6-8-21)15-25(31)30-12-9-23(10-13-30)28-24-4-2-3-22(26)16-24/h2-8,16,19,23,27-28H,9-15,17-18H2,1H3/t19-/m0/s1
InChIKey RZKDEGZIFSJVNA-IBGZPJMESA-N
SMILES C[C@H]1CN(CC2=CC=C(CC(N3CCC(NC4=CC=CC(F)=C4)CC3)=O)C=C2)CCN1
Reference

</br> 1: Barshop K, Kuo B. The investigational drug camicinal for the treatment of gastroparesis. Expert Opin Investig Drugs. 2015 Jan;24(1):133-140. Epub 2014 Oct 24. PubMed PMID: 25341626.

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